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<span>PH計如何按藥典測PH值確定是否弱緩沖液？</span></p> </div>   <div id="dnfsbur" class="ly_NyNewsdetail"> <h1 class="NyNewsdetail_title">PH計如何按藥典測PH值確定是否弱緩沖液？</h1> <div id="zp9pqjr" class="NyNewsdetail_tips">更新時(shí)間：2014-10-22 點(diǎn)擊次數：9973</div> <div id="ejc7jxp" class="NyNewsdetail_con"> <p>對于PH值的測定，藥典里特別指出，“對弱緩沖液或無(wú)緩沖作用溶液的PH值測定"要有別于一般溶液的測定方法。<br><br>但是，怎么樣的溶液才能稱(chēng)為“弱緩沖液或無(wú)緩沖作用溶液"呢？<br><br>比如一種注射液產(chǎn)品，如果輔料只是注射用水，那應該是“弱緩沖液或無(wú)緩沖作用溶液"吧，但如果用弱酸/堿或緩沖對調節過(guò)PH的注射液產(chǎn)品呢？<br><br>我想知道的是進(jìn)行過(guò)那種程度的PH調節可以稱(chēng)之為“弱緩沖液或無(wú)緩沖作用溶液"，還是只要有調節過(guò)PH值就不能成為“弱緩沖液或無(wú)緩沖作用溶液"？對于后者，如果調節至7.0左右也不能認定嗎？<br><br>首先，緩沖能力是針對包括藥物在內的整個(gè)溶液體系而言，所以對于注射用水，大家都知道沒(méi)什么緩沖能力的。緩沖能力可以通過(guò)向體系中加入少量的酸或堿考察pH值是否變化劇烈，國內好像有個(gè)關(guān)于新版藥典培訓的PPT中曾經(jīng)提到。對于注射用品，我覺(jué)得加入緩沖溶液后一般都會(huì )增大它的緩沖能力，可能在穩定性方面有好處吧<br><br></p> </div> <div id="is2wihi" class="ly_PrevNext"> <ul> <li>上一篇：<a href="/Article-596249.html">實(shí)驗室PH計長(cháng)時(shí)間不用校正問(wèn)題</a></li> <li>下一篇：<a 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